Melbourne, Australia, (ANTARA/PRNewswire) - Telix Pharmaceuticals Limited (ASX: TLX, Telix, the Company) today announces presentations featuring the Company's theranostic programs at the upcoming American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU 2024) to be held in San Francisco, CA (US) from 25 – 27 January 2024.

Dr David N. Cade, Telix Group Chief Medical Officer, said, "We are pleased to present updates on our late-stage therapeutic programs for prostate and kidney cancer at ASCO GU 2024, the leading specialised event for GU cancer care worldwide.

"The ProstACT GLOBAL study of TLX591 (¹⁷⁷Lu rosopatamab tetraxetan) will be presented, the first Phase III trial to evaluate TLX591, our lead radio-antibody drug conjugate (rADC) therapy candidate in patients with PSMA-positive metastatic castrate-resistant prostate cancer (mCRPC).

"Data from the recently completed Phase I ProstACT SELECT study will also be showcased, confirming the clinical validity of Telix's optimal fractionated dosing and product safety profile.^[1] Both ProstACT studies are exploring TLX591 administered together with real-world standard of care, differentiating this program from other PSMA studies and reflecting Telix's continued innovation in prostate cancer care and commitment to patient outcomes.

"Eric Jonasch MD, will present the STARLITE-1 investigator-initiated trial of Telix's therapy candidate, TLX250 (¹⁷⁷Lu girentuximab), in combination with immunotherapy in clear cell renal cell carcinoma, the most common and aggressive form of kidney cancer.

"We look forward to seeing you at our booth to discuss Telix's industry leading theranostic pipeline, our associated medical devices, and opportunities for collaboration."

ASCO GU 2024 presentation details are listed below: 

Track: Prostate Cancer- Advanced | Prostate Cancer- Localized
Type: Trials in Progress Poster Session
Title: ProstACT SELECT: Safety, tolerability, and dosimetry of TLX591 with best standard of care in patients with PSMA-expressing metastatic castration-resistant prostate cancer
ClinicalTrials.gov ID: NCT04786847  
Location: Level 1, West Hall | On Demand
Date and Time: January 25, 2024 | 11:30 AM – 1:00 PM (PT)
Presenter: Nat Lenzo MD, GenesisCare, AUSTRALIA
Abstract: TPS253
Poster Bd: Q14

Track: Prostate Cancer- Advanced | Prostate Cancer- Localized
Type: Trials in Progress Poster Session
Title: ProstACT GLOBAL: A Phase III study of best standard of care with and without TLX591 for patients with PSMA-expressing metastatic castration-resistant prostate cancer progressing despite prior treatment with a novel androgen axis drug
ClinicalTrials.gov ID: NCT04876651
Location: Level 1, West Hall | On Demand
Date and Time: January 25, 2024 | 11:30 AM – 1:00 PM (PT)
Presenter: Brenda Cerqueira, Telix Pharmaceuticals, North Melbourne, AUSTRALIA
Abstract: TPS256
Poster Bd: Q17

Track: Renal Cell Cancer, Adrenal Cancer, Penile Cancer, Testicular Cancer, Urethral Cancer
Type: Trials in Progress Poster Session
Title: STARLITE-1: A Phase Ib/II study of combination 177Lu girentuximab plus cabozantinib and nivolumab in treatment naive patients with advanced clear cell RCC
ClinicalTrials.gov ID: NCT05663710
Location: Level 1, West Hall | On Demand
Date and Time: January 27, 2024 | 7:00 AM – 8:10 AM, 11:30 AM – 1:00 PM (PT) 
Presenter: Eric Jonasch MD, The University of Texas, MD Anderson Cancer Center, Houston, TX
Abstract: TPS496
Poster Bd: M17

About Telix Pharmaceuticals Limited

Telix is a biopharmaceutical company focused on the development and commercialisation of diagnostic and therapeutic radiopharmaceuticals and associated medical devices. Telix is headquartered in Melbourne, Australia with international operations in the United States, Europe (Belgium and Switzerland), and Japan. Telix is developing a portfolio of clinical-stage products that aims to address significant unmet medical needs in oncology and rare diseases. Telix is listed on the Australian Securities Exchange (ASX: TLX).

Visit www.telixpharma.com for further information about Telix, including details of the latest share price, announcements made to the ASX, investor and analyst presentations, news releases, event details and other publications that may be of interest. You can also follow Telix on X and LinkedIn.

Telix's lead imaging product, gallium-68 (⁶⁸Ga) gozetotide injection (also known as ⁶⁸Ga PSMA-11 and marketed under the brand name Illuccix^®), has been approved by the U.S. Food and Drug Administration (FDA),^[2] by the Australian Therapeutic Goods Administration (TGA),^[3] and by Health Canada.^[4]

Telix Investor Relations

Ms. Kyahn Williamson
Telix Pharmaceuticals Limited
SVP Investor Relations and Corporate Communications
Email: kyahn.williamson@telixpharma.com

Legal Notices

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Source: Telix Pharmaceuticals Limited